In this work studied is the synergistic effect of asymmetric bistable coupled network systems under the action of Gaussian colored noise and periodic signal. The system is a network model consisting of a large number of oscillators. The interaction and change between individuals produce complex nonlinear behavior patterns. For further research, firstly, the original N-dimensional system is reduced and approximated by using the mean field theory, the unified colored noise approximation theory and the equivalent nonlinearization method. Secondly, the Langevin equation of simplified model is obtained through the slaving principle by using the two-state model theory to derive the theoretical expression of signal-to-noise ratio. It is found that the system produces the phenomenon of scale stochastic resonance. Finally, the effects of Gaussian color noise parameters, system parameters and periodic signal parameters on the stochastic resonance behavior of asymmetric coupled network systems are discussed. The results show that the increase of Gaussian colored noise correlation time and noise intensity can promote the scale stochastic resonance phenomenon; selecting appropriate coupling coefficient can achieve the optimal stochastic resonance effect. And the stochastic resonance phenomenon of the system driven by the Gaussian colored noise and the Gaussian white noise, respectively, are analyzed and compared with each other. Research result shows that Gaussian colored noise is more conducive to enhancing stochastic resonance phenomenon.