Internal solitary waves exist widely in the oceans, and their generations, propagation evolutions, and dissipations have profound effects on the ocean environment, topography, and marine structures. Typically, two basic theoretical models are now being developed to govern the evolutions of internal solitary waves at the interface of two immiscible inviscid fluids. One is a unidirectional wave propagation model described by the KdV (Korteweg-de Vries) equation, and the other is a bidirectional wave propagation model depicted by the Miyata-Choi-Camassa (MCC) equation. Neither of them, however, can effectively characterize the course of the evolution of large-amplitude internal solitary wave. In this paper, a modified unidirectional internal solitary wave model is established by adjusting the coefficients of the original unidirectional model. The adjusted coefficients are determined through asymptotic analysis by matching with the MCC model. The efficacy of the modified coefficients is investigated by comparing the modified model with the original model. The experiments on the generation of internal solitary waves with varying amplitudes are carried out by comparing the internal solitary wave solution of the modified equation. It is shown that the modified model is suitable for describing the waveform of internal solitary waves with small, medium, and large amplitudes within the limiting amplitude of the MCC model. By quantitatively analyzing the agreement of the effective wavelength, wave speed, and waveform of steady-state internal solitary waves between the unidirectional model and the MCC model, the applicability of the modified model in characterization of the properties of steady-state internal solitary waves is further investigated. In addition, the stability of unidirectional theoretical model is analyzed for simulating the propagation of large-amplitude internal solitary wave under flat bottom condition. It is found that the unidirectional model is suitable for initiating its own internal solitary solution provided that the numerical scheme is stable. It is shown that the modified unidirectional model can be used to characterize large-amplitude internal solitary waves, and is also expected to be applied to the study of marine structure hydrodynamics.