According to the principle of dielectrophoresis, an aspherical double-liquid lens based on parallel plate electrodes is designed. In comparison with the liquid lenses based on patterned-electrodes, the aspherical double-liquid lens structure uses continuous electrodes, which have the advantages of simpler processing, lower cost, easier realization and more practicability. The droplet in the dielectric electrophoretic liquid lens is polarized in the electric field and moves towards the higher electric field intensity under the action of the dielectrophoretic force. With the change of applied voltage, the dielectrophoretic force varies, thus the contact angle of the droplet at the liquid-liquid interface is changed. Firstly, the models of aspherical double-liquid lenses under different voltages are established with Comsol software, and the data of interfacial profile are derived. Then using Matlab software, the derived interface surface data are fitted by polynomial, and the aspherical coefficients are obtained. Finally, the optical models are built with Zemax software, and the variation range of focal length and root mean square (RMS) radius of aspherical double-liquid lens under different voltages are analyzed. In order to further study the characteristics of aspherical double-liquid lens, it is compared with spherical double-liquid lens model. The liquid material, cavity structure and droplet volume of spherical double-liquid lens are consistent with those of aspherical double-liquid lens. The corresponding spherical double-liquid lens model is established by using the Zemax software, the range of focal length and RMS radius of spherical double-liquid lens under different voltages are obtained. The results show that the focal length variation range of aspherical double-liquid lens is larger than that of spherical double-liquid lens, and the imaging quality of the former is better than that of the latter. The experimental preparation of the designed aspherical double-liquid lens device is carried out, and its focal length and imaging resolution are measured. When the operating voltage is in a range of 0–280 V, the focal length varies from 54.2391 to 34.5855 mm, which is basically consistent with the simulation result. The feasibility of the liquid lens structure is verified experimentally. The imaging resolution can reach 45.255 lp/mm. The designed aspherical double-liquid lens based on the parallel plate electrode can provide a new scheme for the high-quality imaging of liquid lens and its application, and can expand the application scope of liquid lens.