In the study of the gas detectors, it is an important calibration method to use the ultraviolet (UV) laser with two-photon ionization mechanism for producing ionized signal. In the last decades, micro pattern gas detector, especially gaseous electron multiplier and micromesh gaseous detector, has been widely used in high energy experiments. These kinds of gaseous detectors have the advantages of higher ion backflow suppression ability, smaller E× Beffect and good radiation resistance under the relatively higher count rate environment. To obtain a higher spatial resolution with a UV laser calibration system in gaseous electron multiplier detector, two critical technical issues remain to be resolved: the measurability of the laser signal and the accuracy of the laser beam position. In this paper, the studies in simulation and experiment are conducted to discuss these two critical questions. In the simulation section, the simulation results provide an estimation of signal in the gaseous electron multiplier detector with UV laser of 266 nm wavelength in the mixture working gases of Ar/CO ₂(70/30), and give an evaluation of the laser pointing accuracy and the possible relative error of the electron drift velocity. In the experiment section, a UV laser calibration prototype is designed and developed. A pulsed laser of 266 nm wavelength is used as a signal source, which has a Gaussian-like cross section with a frequency of 10 Hz. The experimental results indicate that the signal of the UV laser in a triple gaseous electron multiplier detector reaches 400 mV for a readout strip width of 6 mm, a gain of detector of 5000, and a gain of amplifier of 10 mV/fC. For the calibration laser, the angle accuracy is discussed and tested. The angle uncertainty of the laser can be kept under 5′, and the accuracy of the drift velocity can reach 6.4 × 10 ⁻⁴with a shift of 0.33 mm in the zdirection when the laser beam transmits a distance of 400 mm in the gas chamber. All of these results show that the laser beam specific parameters are the main reference for designing the prototype detector. According to the optimal parameters, a gaseous prototype detector will be tested in the next study.