Optical path design of high power laser facilities should consider several optimization measures such as those that are related to image transmission, ghost avoidance, and stray light management. According to the diffraction optical propagation theory, we study the the influences of wavefront characteristics of large aperture optical components on optimizing the design parameters of optical path in view of increasing the output load. The results show that the arrangement interval of the last stage optical drive can be very useful in improving the output load of the laser facilities if it is controlled to be over 6 m long. In general, a large aperture optical element with a phase error peak value of 0.34 can reduce the near field beam quality of a high-power laser by about 10% and give rise to a maximum decrease of about 21% when the phase error reaches 1.36. Superposition of multiple optical elements with different phase error distribution characteristics can reduce the negative effect of the mid frequency phase error. However, the nonlinear effect of large aperture optical components can aggravate the influence of the intermediate frequency phase error on the damage resistance capacity of the device. Under the premise that the damage threshold of the large caliber optical element is limited to 20 J/cm2, the using of a laser facility with a compact optical path, with an input laser energy density controlled to be below 16.8 J/cm2, will avoid damaging the optical components efficiently. A relatively flexible optical layout can further increase the average energy density of the final output laser and is very beneficial to the enhancing of the output load capacity of the laser facility.