The photonic crystal fiber has received the widespread attention in the sensing field because of its flexible structure and unique features. A refractive index and temperature sensor based on the D-shaped photonic crystal fiber is designed and analyzed. In the side section of the D-shaped photonic crystal fiber, a coat with a gold film is used as a surface plasmon resonance (SPR) sensing channel for measuring the refractive index of liquid determinand. Temperature sensitive liquid-toluene is filled in an air hole A as a directional coupling sensing channel to realize the temperature measurement. When the SPR mode and guided mode satisfy the phase matching condition, the SPR effect is produced. Most of the core energy is transferred to the metal film layer in the surface, and then the loss of guided mode in the fiber core will grow. Therefore, the shift of the SPR peak position can be used to measure the refractive index of the determinand indirectly. When the wave mode in the thermosensitive liquid-toluene can achieve phase matching with the guided mode, the directional coupling effect occurs, and then the wavelength of the absorption peak position can be used to measure the change of temperature indirectly. Based on further numerical simulation, the peak position of directional coupling is not changed by the refractive index of the determinand, and the SPR peak position is not shifted by the temperature change either. As these two sensing mechanisms can be distinguished easily, the refractive index and temperature sensing are simultaneously realized. The characteristics of the sensor are simulated numerically by using a full vector finite element method under the boundary condition of anisotropic perfectly matched layer. From the analysis of the D-shaped photonic crystal fiber structure parameters, we find that the diameter d of air hole plays an important role in the directional coupling absorption peak position and temperature sensitivity. For the SPR peak, its position is only affected by the thickness t of gold film, and its relative intensity is changed with the diameter d of air hole and grinding depth d1. The results show that when the temperature ranges from -10 ℃ to 80 ℃, the temperature sensitivity reaches 11.6 nm/℃, and when the refractive index is in a range from 1.32 to 1.44, its sensitivity reaches 26000 nm/RIU.