A type of structural equation, new exact and approximate conserved quantity which are deduced from Mei symmetry of Lagrange equations for a weakly nonholonomic system, are investigated. First, Lagrange equations of weakly nonholonomic system are established. Next, under the infinitesimal transformations of Lie groups, the definition and the criterion of Mei symmetry for Lagrange equations in weakly nonholonomic systems and its first-degree approximate holonomic system are given. And then, the expressions of new structural equation and new exact and approximate conserved quantities of Mei symmetry for Lagrange equations in weakly nonholonomic systems are obtained. Finelly, an example is given to study the question of the exact and the approximate new conserved quantities.