It is of significance in engineering to achieve stochastic resonance of periodic signal with large frequency by turning the parameters of a bistable system. The normalization transform of bistable system parameter is deduced. Stochastic resonance of periodic signal with large parameters is exhibited by numerical simulation based on the proposed normalization transform, by which an arbitrary high frequency periodic signal can be processed. Analog circuit is used to verify the stochastic resonance happening in the bistable system with large parameters. The mechanism of realizing a periodic signal with large parameters by twice sampling stochastic resonance is analyzed, which is compared with normalization transform method through numerical simulation. The simulation results show that the numerical solution of twice sampling stochastic resonance is prone to being unstable with the variation of mixed input signal amplitude, while the normalization transform method possesses more stability and adaptability.