One-way deterministic secure quantum communication protocol based on single photons is proposed in this paper, in which the XOR operation by bits of the information sequence and random sequence is performed and the checking sequence is inserted before the sender’s coding operation. When the photons arrive at the receiver, they are delayed at the receiver, and the sender then publishes the coding basis, so the photons can be measured in the correct basis. Then the two parties estimate the security of the quantum channel by the checking bits. When the channel is secure the sender publishes the random bits where the receiver has results, and the information sequence can be recovered by the receiver. Even the channel is not secure, what the eavesdropper gets is the random sending sequence, the information sequence is still secure. This protocol has the advantages of higher transmission efficiency and easier implementation compared with the two-way communication.