This paper analyzes the properties of the quantum conditional amplitude operator.This operator plays a role similar to that of the conditional probability in classical information theory.One argues that the spectrum of the conditional operator that characterizes a quantum bipartite system is invariant under local unitary transformations,and shows its inseparability.It is proven that the conditional amplitude operator of a separable state cannot have an eigenvalue exceeding unity.A related separability condition based on the non-negativity of the von Neumann conditional entropy is obtained.