Fisher information is an important concept in estimation theory, which has recently been found closely related with the criteria of the entanglement in quantum information. Under the condition of non-rotating wave approximation, the classical phase space of the Dicke model displays chaotic dynamic properties. This paper studies the quantum Fisher information and the dynamic properties of spin squeezing in the interaction system of light and matter described in the Dicke model. Results reveal that, in the short-time instant state, wherever the initial state is, in a regular region or a chaotic region, the system displays entanglement; but in the long-time stable state, when the initial state is in the regular region, the system entanglement disappears, however, when the initial state is in the chaotic region, the system is always entangled. Compared with the spin-squeezing dynamic properties of the system, Fisher information is found to be able to effectively characterize quantum chaos. On further examination on the dynamic evolvement properties of the density matrix and purity of the system when in the regular and chaotic regions, we find that chaos gives rise to decoherence of the system, showing that quantum information become more sensitive to chaos.