The dynamic equation of relative rotation nonlinear dynamic system with Mathieu-Duffing oscillator is investigated. Firstly, the bifurcation response align of the relative rotation system under primary resonance-basic parameters condition is deduced using the method of multiple scales, and a singularity analysis is employed to obtain the transition set of steady motion. Secondly, a global bifurcation of the system, some probable routes leading to chaos and multiple times leading to chaos with parametric and external excitation amplitude changes have been discussed by using Melnikov method, and the necessary condition for chaotic motion of the system is presented. Finally, a numerical method is employed to further prove the effectiveness of the theoretical research.