An interesting fact in digital holography is that the reconstruction process of the hologram recorded by the color camera may result in some periodic distribution of images in the image plane. In this paper we describe the production mechanism, characteristics and application of image periodicity in digital hologram reconstruction. Our study shows that the image distribution characteristics in the hologram reconstruction are strongly dependent on the option of RGB sampling mode due to a color filter array being used in the CCD camera, and the relevant demosaicing process of the sampling array reconstruction. The image and the dc noise from the hologram reconstruction may be of different distribution patterns due to the modulation function in the inverse Fourier transform of a full monochromatic sampling array (MSA) with demosaicing. Thus, this work reveals the potential relationship between the demosaicing algorithm for a full MSA reconstruction, the sampling frequency in the hologram recording, and the image periodicity in the hologram reconstruction. Finally the application of the image periodicity in zero-order noise suppression is discussed.