A series of polycrystaline bulk samples of (La1-yTby)0.67Sr0.33MnO3(y=0,0.05,0.15,0.20,0.25,0.33,0.40,0.50,0.60,1.00) have been prepared by solid-phase reaction sintering. X-ray diffraction patterns show that the rhombohedral structure has been transfered into orthorhombic structure with increasing Tb content y. For the sample with y=0.40, a colossal magnetoresistance up to 900% has been observed at 180K. When μ0H=1.7T, the anisotropic magnetostriction (λt) of -50×10-6 and volume magnetostriction (ω) -130×10-6 have been observed for the samples of y=0.20 at room temperature, and y=0.33 at 210K respectively.